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A14747 trans-3-(3-Pyridyl)acrylic acid, 99%

CAS Number
19337-97-4
Synonyms
3-(3-Pyridine)acrylic acid

Stock No. Size Price ($) Quantity Availability
A14747-06 5g 26.30
A14747-14 25g 108.00
A14747-30 250g 806.00
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trans-3-(3-Pyridyl)acrylic acid, 99%

MDL
MFCD00006410
EINECS
214-424-0

Chemical Properties

Formula
C8H7NO2
Formula Weight
149.15
Melting point
232-235°
Storage & Sensitivity
Ambient temperatures.

Applications

trans-3-(3-Pyridyl)acrylic acid is a useful synthetic intermediate. It is also used to prepare aminomethyl benzimidazoles, which acts as an inhibitor of gelatinase B. Further, it is used in the preparation of aminopyridines as antibacterial enoyl acyl carrier protein reductase inhibitors.

Notes

Incompatible with oxidizing agents, acids and bases.

Literature References

Singha, D. K.; Mahata, P. Luminescent coordination polymer-fullerene composite as a highly sensitive and selective optical detector for 2,4,6-trinitrophenol (TNP). RSC Adv. 2015, 5 (36), 28092-28097.

Sun, X.; Zhang, L.; Zhang, H.; Qian, H.; Ji, J.; Tang, L.; Li, Z.; Zhang, G. Electrochemical detection of 8-hydroxy-2'-deoxyguanosine as a biomarker for oxidative DNA damage in HEK293 cells exposed to 3-chloro-1,2-propanediol. Anal. Methods 2015, 7 (16), 6664-6671.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
113290
Harmonized Tariff Code
2933.39
TSCA
No

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