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2-(Trifluoromethyl)phenylhydrazine is used as an intermediate in organic syntheses. It is also ued as a fine chemical intermediate, GC derivatizing agent, coupling reagent and N- protecting agent.
C Kunick.; C Schultz.; T Lemcke.; DW Zaharevitz. 2-Substituted paullones: CDK1/cyclin B-inhibiting property and in vitro antiproliferative activity. Bioorganic & Medicinal Chemistry Letters. 1999, 10 (6), 567-569.
H Jiang.; Y Wang.; W Wan.; J Hao. p-TsOH promoted Fischer indole synthesis of multi-substituted 2-trifluoromethyl indole derivatives. Tetrahedron. 2010, 10 (6), 567-569.
Hazard Statements: H301-H311-H332-H315-H319-H335
Toxic if swallowed. Toxic in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.