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2- Chloropyridine is used as an intermediate chemical in the production of various pyrithione, for use in cosmetics, personal care products and pharmaceutical products.
Sabine Choppin.; Philippe Gros.; Yves For. Unusual C-6 Lithiation of 2-Chloropyridine-Mediated by BuLi-Me2N(CH2)2OLi. New Access to 6-Functional-2-chloropyridines and Chloro-bis-heterocycles. Org. Lett. 2002, 2, (6), 803-805.
Meriç Bakiler.; I.V. Maslov.; Sevim Akyüzc.Theoretical study of the vibrational spectra of 2-chloropyridine metal complexes. I. Calculation and analysis of the IR spectrum of 2-chloropyridine. Journal of Molecular Structure. 1999, 475, (1), 83-92.
Reaction with the unimetal suberbase complex formed from 2 mol of n-BuLi and I mol of 2-(Dimethylamino)ethanol, B23616, in hexane, gives products resulting from apparent metallation at the 6-position, providing useful access to 6-functionalized 2-chloropyridines: Org. Lett., 2, 803 (2000). See also 2-Methoxypyridine, A13675, for a similar effect.
Hazard Statements: H227-H302-H310-H315-H318-H330-H373
Combustible liquid. Harmful if swallowed. Fatal in contact with skin. Causes skin irritation. Causes serious eye damage. Fatal if inhaled. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P210-P235-P260-P262-P264b-P270-P271-P280-P284-P301+P312-P302+P350-P304+P340-P305+P351+P338-P310-P314-P330-P332+P313-P361-P363-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Do not breathe dust/fume/gas/mist/vapours/spray. Do not get in eyes, on skin, or on clothing. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. Wear respiratory protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Gently wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Get medical advice/attention if you feel unwell. Rinse mouth. If skin irritation occurs: Get medical advice/attention. Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant