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Tri-n-butylamine is an important intermediate in the production of phase transfer catalysts like tributylmethylammonium chloride and tributylbenzylammonium chloride. It is also used in pharmaceuticals, agrochemicals, surfactants, lubricant additives, vulcanization accelerators and dyes. It acts as a catalyst and as a solvent in organic syntheses and polymerization reactions. It serves as a strong base anion exchanger, acid acceptor, inhibitor in hydraulic fluids and an emulsifying agent. Further, it is used to prepare photographic chemicals.
Nakajima, M.; Fava, E.; Loescher, S.; Jiang, Z.; Rueping, M. Photoredox-Catalyzed Reductive Coupling of Aldehydes, Ketones, and Imines with Visible Light. Angew. Chem. Int. Ed. 2015, 54 (30), 8828-8832.
Sarac, I.; Meier, C. Efficient Automated Solid-Phase Synthesis of DNA and RNA 5'-Triphosphates. Chem. Eur. J. 2015, 21 (46), 16421-16426.
Hazard Statements: H227-H302-H310-H330-H315-H319
Combustible liquid. Harmful if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: P304+P340-P305+P351+P338-P320-P330-P405-P501a
IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.