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3-Amino-1,2,4-triazole is an inhibitor of mitochondrial and chloroplast function. Commercial grade 3- amino-1,2,4-triazole (which generally contains catalase anti-inhibitory impurities) is used as a cotton defoliant.
Kailash C. Bhuyan.; Durga K. Bhuyan. Regulation of hydrogen peroxide in eye humors effect of 3-amino-1H-1,2,4-triazole on catalase and glutathione peroxidase of rabbit eye. Biochimica et Biophysica Acta (BBA) - General Subjects. 1977, 497, (3), 641-651.
Grant R. Krow .; James T. Carey .; David E. Zacharias .; Edward E. Knaus. Reexamination of stereochemical issues concerning 2-phenyl-1,2-dihydropyridine-maleimide cycloadditions. J. Org. Chem. 1982, 47, (11), 1989-1993.
Hazard Statements: H302-H319-H350-H360-H373
Harmful if swallowed. Causes serious eye irritation. May cause cancer. May damage fertility or the unborn child. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P201-P202-P260-P264b-P270-P280i-P281-P301+P312-P305+P351+P338-P308+P313-P330-P337+P313-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear eye/face protection. Use personal protective equipment as required. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. If eye irritation persists: Dispose of contents/ container to an approved waste disposal plant