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tert-Butyl bromoacetate is used as an intermediate in the production of dyes, pharmaceuticals, agrochemicals and in organic compounds. It finds application as an alkylating agent. It plays an important role to prepare (2-oxo-4-vinyl-azetidin-1-yl)-acetic acid tert-butyl ester and in collagenase inhibitors synthesis.
Becherer, T.; Grunewald, C.; Engelschalt, V.; Multhaup, G.; Risse, T.; Haag, R. Polyglycerol based coatings to reduce non-specific protein adsorption in sample vials and on SPR sensors. Anal. Chim. Acta 2015, 867, 47-55.
Kamalov, M.; Harris, P. W.; Hartinger, C. G.; Miskelly, G. M.; Cooper, G. J.; Brimble, M. A. Physicochemical studies on the copper(II) binding by glycated collagen telopeptides. Org. Biomol. Chem. 2015, 13 (10), 3058-3063.
Hazard Statements: H226-H302-H314-H318
Flammable liquid and vapour. Harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P280-P303+P361+P353-P305+P351+P338-P310a
Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor