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617-35-6 - Ethyl pyruvate, 98% - Pyruvic acid ethyl ester - Ethyl 2-oxopropionate - A15045 - Alfa Aesar

A15045 Ethyl pyruvate, 98%

CAS Number
617-35-6
Synonyms
Pyruvic acid ethyl ester
Ethyl 2-oxopropionate

Size Price ($) Quantity Availability
50g 32.58
250g 103.20
500g 206.10
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Ethyl pyruvate, 98%

MDL
MFCD00009123
EINECS
210-511-2

Chemical Properties

Formula
C5H8O3
Formula Weight
116.12
Melting point
-58°
Boiling Point
143-145°
Flash Point
45°(113°F)
Density
1.050
Refractive Index
1.4050
Solubility
Miscible with water, ethanol and ether.

Applications

Ethyl pyruvate is used as a flavoring agent in food and anti-inflammatory agent for the treatment of critical inflammatory conditions. It is used in the treatment of critical illnesses such as severe sepsis, acute respiratory distress syndrome, burn injury, acute pancreatitis and stroke. It plays an important role in cardiac function after coronary ischemia and reperfusion.

Notes

Store in a cool place. Incompatible with oxidizing agents.

Literature References

Stanisavljevi?, S.; Jevti?, B.; Djedovi?, N.; Miljkovi?, D. Short term exposure to ethyl pyruvate has long term anti-inflammatory effects on microglial cells. Biomed. Pharmacother. 2015, 72, 11-16.

Jiang, Z.; Li, X.; Lin, Z.; Chen, J.; Guan, X.; Chen, M. Ethyl pyruvate reduces hepatic mitochondrial swelling and dysfunction in a rat model of sepsis. Int. J. Clin. Exp. Pathol. 2015, 8 (7), 7774-7785.

GHS Hazard and Precautionary Statements

Hazard Statements: H226

Flammable liquid and vapour.

Precautionary Statements: P210-P280-P240-P241-P233-P242-P243-P303+P361+P353-P403+P235-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Keep container tightly closed. Use only non-sparking tools. Take precautionary measures against static discharge. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,8021
Beilstein
1071466
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2918.30
TSCA
Yes

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