2-Imino-4-thiobiuret is used in the design and synthesis of guanylthiourea derivatives which are potential inhibitors of plasmodium falciparum dihydrofolate reductase enzyme. 2-Imino-4-thiobiuret is also used as a reagent in recyclization reactions of N-arylmaleimides with polynucleophilic compounds.
V D Luk'ianchuk; and L V Savchenkova. Antihypoxants: their status and outlook. Anesteziologiia i reanimatologiia, 1998, 250-55.
G A Boiarinov et. al. Effect of using gutimine in the pre-ischemic period on myocardial phospholipids during reperfusion. Voprosy Meditsinskoi Khimi, 1993, 39(4), 34-38.
Hazard Statements: H302-H361
Harmful if swallowed. Suspected of damaging fertility or the unborn child.
Precautionary Statements: P280h-P330-P501a
Wear protective gloves/clothing. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.