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A15134 2-Dimethylaminoethyl chloride hydrochloride, 98+%

CAS Number
4584-46-7
Synonyms
1-Chloro-2-(dimethylamino)ethane hydrochloride
N-(2-Chloroethyl)-N,N-dimethylammonium chloride

Stock No. Size Price ($) Quantity Availability
A15134-22 100g 17.10
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2-Dimethylaminoethyl chloride hydrochloride, 98+%

MDL
MFCD00012516
EINECS
224-970-1

Chemical Properties

Formula
ClCH2CH2N(CH3)2•HCl
Formula Weight
144.05
Melting point
205-208°
Storage & Sensitivity
Hygroscopic. Ambient temperatures.
Solubility
Soluble in water (2000 mg/ml at 20°C), and alcohol.

Applications

2-Chloro-N,N-dimethylethylamine is a widely used as a intermediate and starting reagent for organic synthesis. Also acts as Intermediate for the syntheses of bephenium hydroxynaphthoate, diltiazem, mepyramine and phenyltoloxamine.

Notes

Hygroscopic, store away from moisture. Store in cool, dry place in tightly closed container. Store away from oxidizing agent. Store under dry inert gas.

Literature References

Ali A. El-Emam; Omar A. Al-Deeb; Mohamed Al-Omar; Jochen Lehmann. Synthesis, antimicrobial, and anti-HIV-1 activity of certain 5-(1-adamantyl)-2-substituted thio-1,3,4-oxadiazoles and 5-(1-adamantyl)-3-substituted aminomethyl-1,3,4-oxadiazoline-2-thiones. Bioorganic & Medicinal Chemistry., 2004, 12(19), 5107-5113.

Harvey Gurien. Reaction of 2-Dimethylaminoethyl Chloride with Magnesium. J. Org. Chem., 1963, 28(3), 878-879.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H311-H315-H320-H335-H341-H372

Toxic if swallowed. Toxic in contact with skin. Causes skin irritation. Causes eye irritation. May cause respiratory irritation. Suspected of causing genetic defects. Causes damage to organs through prolonged or repeated exposure.

Precautionary Statements: P201-P202-P260-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P308+P313-P312-P330-P332+P313-P337+P313-P362-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. If skin irritation occurs: If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
3591234
Hazard Class
9
Packing Group
III
Harmonized Tariff Code
2921.12
TSCA
Yes
RTECS
KQ9020000

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