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4584-46-7 - 2-Dimethylaminoethyl chloride hydrochloride, 98+% - 1-Chloro-2-(dimethylamino)ethane hydrochloride - N-(2-Chloroethyl)-N,N-dimethylammonium chloride - A15134 - Alfa Aesar

A15134 2-Dimethylaminoethyl chloride hydrochloride, 98+%

CAS Number
4584-46-7
Synonyms
1-Chloro-2-(dimethylamino)ethane hydrochloride
N-(2-Chloroethyl)-N,N-dimethylammonium chloride

Size Price ($) Quantity Availability
100g 14.85
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2-Dimethylaminoethyl chloride hydrochloride, 98+%

MDL
MFCD00012516
EINECS
224-970-1

Chemical Properties

Formula
ClCH2CH2N(CH3)2•HCl
Formula Weight
144.05
Melting point
205-208°
Sensitivity
Hygroscopic
Solubility
Soluble in water (2000 mg/ml at 20°C), and alcohol.

Applications

2-Chloro-N,N-dimethylethylamine is a widely used as a intermediate and starting reagent for organic synthesis. Also acts as Intermediate for the syntheses of bephenium hydroxynaphthoate, diltiazem, mepyramine and phenyltoloxamine.

Notes

Hygroscopic, store away from moisture. Store in cool, dry place in tightly closed container. Store away from oxidizing agent. Store under dry inert gas.

Literature References

Ali A. El-Emam; Omar A. Al-Deeb; Mohamed Al-Omar; Jochen Lehmann. Synthesis, antimicrobial, and anti-HIV-1 activity of certain 5-(1-adamantyl)-2-substituted thio-1,3,4-oxadiazoles and 5-(1-adamantyl)-3-substituted aminomethyl-1,3,4-oxadiazoline-2-thiones. Bioorganic & Medicinal Chemistry., 2004, 12(19), 5107-5113.

Harvey Gurien. Reaction of 2-Dimethylaminoethyl Chloride with Magnesium. J. Org. Chem., 1963, 28(3), 878-879.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H311-H315-H319-H335

Toxic if swallowed. Toxic in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P301+P310-P305+P351+P338-P361-P304+P340-P362-P312-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Remove/Take off immediately all contaminated clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
3591234
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2921.19
TSCA
Yes
RTECS
KQ9020000

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