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130-85-8 - Pamoic acid, 99% - Embonic acid - 4,4'-Methylenebis(3-hydroxy-2-naphthoic acid) - A15207 - Alfa Aesar

A15207 Pamoic acid, 99%

CAS Number
130-85-8
Synonyms
Embonic acid
4,4'-Methylenebis(3-hydroxy-2-naphthoic acid)

Size Price ($) Quantity Availability
50g 40.53
250g 111.20
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Pamoic acid, 99%

MDL
MFCD00004079
EINECS
204-998-0

Chemical Properties

Formula
C23H16O6
Formula Weight
388.38
Melting point
>300°
Solubility
Soluble in nitrobenzene, pyridine

Applications

Pamoic acid is used in preparation of repository derivatives of medicinal agents, used in pharmacology to increase the solubility of a drug in water.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Kristof Prinsen.; Junjie Li.; Hubert Vanbilloen.; Peter Vermaelen.; Ellen Devos.; Luc Mortelmans.; Guy Bormans.; Yicheng Ni.; Alfons Verbruggen. Development and evaluation of a 68Ga labeled pamoic acid derivative for in vivo visualization of necrosis using positron emission tomography. Bioorganic & Medicinal Chemistry. 2010, 18, (14), 5274-5281.

Miao Du.; Zhi-Hui Zhang.; Wei Guo.; Xiao-Juan Fu. Multi-Component Hydrogen-Bonding Assembly of a Pharmaceutical Agent Pamoic Acid with Piperazine or 4,4?-Bipyridyl: A Channel Hydrated Salt with Multiple-Helical Motifs vs a Bimolecular Cocrystal. Cryst. Growth Des. 2009, 9, (4), 1655-1657.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,7005
Beilstein
901319
Harmonized Tariff Code
2918.29
TSCA
Yes
RTECS
QL2180000

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