Methyl 3,5-dihydroxybenzoate was used in the synthesis of cored dendrimers. It was also used in the preparation of bis(5-carbomethoxy-1,3-phenylene)-32-crown-10, a semi-rigid 32-membered ring diester crown ether. It has been used to study ribonucleotide reductase inhibiton and anti-tumor activity .
Michael S.Wendlan; Steven C.Zimmerman. Synthesis of cored dendrimers. J. Am. Chem. Soc. 1999, 121,(6), 1389-1390.
Yadollah Delaviz; Harry W.Gibson. Macrocyclic polymers. 1. Synthesis of a poly(ester crown) based on bis(5-carboxy-1,3-phenylene)-32-crown-10 and 4,4'-isopropylidenediphenol (bisphenol A). Macromolecules. 1992, 25,(1), 18-20.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.