I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
3-Nitrophenol is used as indicator in 0.3% Soln in 50% alcohol ph: 6.8 Colorless, 8.6 Yellow. It is used in the synthesis of RAGE inhibitors via the etherification of phenols. Also used in the synthesis of kinase inhibitors against epidermal growth factor receptor T790M mutation.
A. Alif; P. Boule; J. Lemaire. Photochemistry and environment XII: Phototransformation of 3-nitrophenol in aqueous solution.Journal of Photochemistry and Photobiology A.1990, 50 331-342.
Mohammad R.Haghighi Podeh; Sanjoy K. Bhattacharya; Mingbo Qu. Effects of nitrophenols on acetate utilizing methanogenic systems.Water Research.1995, 29 391-399.
Acid-base indicator: approx pH 6.6 - 8.6.
Has been used for the formation of active esters. These are more stable than the corresponding 4-nitrophenyl esters, but are sufficiently reactive for use in peptide synthesis: Synthesis, 465 (1979).
Hazard Statements: H302-H315-H318-H373-H500
Harmful if swallowed. Causes skin irritation. Causes serious eye damage. May cause damage to organs through prolonged or repeated exposure. May form combustible dust concentrations in air
Precautionary Statements: P260-P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P310-P314-P330-P332+P313-P362-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Get medical advice/attention if you feel unwell. Rinse mouth. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant