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20260-53-1 - Nicotinoyl chloride hydrochloride, 98% - Pyridine-3-carbonyl chloride hydrochloride - A15317 - Alfa Aesar

A15317 Nicotinoyl chloride hydrochloride, 98%

CAS Number
20260-53-1
Synonyms
Pyridine-3-carbonyl chloride hydrochloride

Size Price ($) Quantity Availability
10g 23.59
50g 78.07
250g 259.20
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Nicotinoyl chloride hydrochloride, 98%

MDL
MFCD00012820
EINECS
243-648-1

Chemical Properties

Formula
C6H4ClNO•HCl
Formula Weight
178.02
Melting point
149-155°
Sensitivity
Moisture Sensitive
Solubility
It decomposes in water.

Applications

Nicotinoyl chloride hydrochloride was used in the preparation of 1-[5-O-tert-butyldimethylsilyl-2-deoxy-2-fluoro-3-O-(3-pyridylcarbonyl)-β-D-ribofuranosyl]uracil, bis(ethylenedithio)tetrathiafulvalene derivatives and 7,16-dinicotinoylated or 7,16-diisonicotinoylated compounds via reaction with tetraaza[14]annulene and its complexes.

Notes

Moisture sensitive. Incompatible with oxidizing agents.

Literature References

K.W.Morin; L.I.Wiebe; E.E.Knaus. Synthesis of brain-targeted 1-(2-deoxy-2-fluoro-beta-D-ribofuranosyl)-(E)-5-(2-iodovinyl)uracil coupled to a dihydropyridine <---> pyridinium salt redox chemical-delivery system. Carbohydrate Research. 1993, 249,(1), 109-116.

 

K.Sakata; M.Itoh. Synthesis and characterization of 7,16-dinicotinoyl- and 7,16-diisonico-tinoyltetraaza[14]annulene and their nickel(II) and copper(II) complexes. Journal of heterocyclic chemistry. 1992, 29,(4), 921-926.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
3655772
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2933.39
TSCA
Yes

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