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A15324 Alloxan monohydrate, 98%

CAS Number
2244-11-3
Synonyms
Mesoxalylurea monohydrate
2,4,5,6(1H,3H)-Pyrimidinetetrone

Stock No. Size Price ($) Quantity Availability
A15324-14 25g 43.90
A15324-18 50g 74.00
A15324-22 100g 125.00
A15324-30 250g 260.00
A15324-0B 1000g 685.00
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Alloxan monohydrate, 98%

MDL
MFCD00149399
EINECS
200-062-0

Chemical Properties

Formula
C4H2N2O4•H2O
Formula Weight
160.09 (142.07anhy)
Melting point
ca 260° dec.
Storage & Sensitivity
Keep Cold. Air Sensitive.
Solubility
Soluble in water, ethanol, acetone, glacial acetic acid and methanol. Slightly soluble in chloroform, petroleum ether, toluene, ethyl acetate and acetic anhydride. Insoluble in ether.

Applications

Cytotoxic compound that causes oxidative base damage to nuclear DNAAlloxan monohydrate is used as a precursor to prepare purple dye murexide. It is also used in research models to induce diabetes and destroy beta cells. Further, it is a strong oxidizing agent and it forms a hemiacetal with its reduced reaction product dialuric acid.

Notes

Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents.

Literature References

Allehyani, B. H.; Elroby, S. A.; Aziz, S. G.; Hilal, R. H. Protonation and deprotonation enthalpies of alloxan and implications for the structure and energy of its complexes with water: a computational study. J. Biomol. Struct. Dyn. 2015, 33 (4), 897-910.

Amraie, E.; Farsani, M. K.; Sadeghi, L.; Khan, T. N.; Babadi, V. Y.; Adavi, Z. The effects of aqueous extract of alfalfa on blood glucose and lipids in alloxan-induced diabetic rats. Interv. Med. Appl. Sci. 2015, 7 (3), 124-128.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H312-H332

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P312-P330-P363-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Rinse mouth. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,282
Beilstein
5309394
Harmonized Tariff Code
2933.59
TSCA
Yes
RTECS
UW0492000

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