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Indole-3-carboxaldehyde is a biochemical used to prepare analogs of the indole phytoalexin cyclobrassinin with NR1R2 group. It was also used as the starting material for the synthesis of higher order indoles including isoindolo[2,1-a]indoles, aplysinopsins, and 4-substituted-tetrahydrobenz[cd]indoles.
Deepa Sinha; Anjani K. Tiwari; Sweta Singh; Gauri Shukla; Pushpa Mishra; Harish Chandra; Anil K. Mishra. Synthesis, characterization and biological activity of Schiff base analogues of indole-3-carboxaldehyde.European Journal of Medicinal Chemistry.2008, 43 160-165.
Robert E. Stutz. Enzymatic Formation of Indole-3-Carboxaldehyde from Indole-3-Acetic Acid.Plant Physiol.1958, 33 (3), 207-212..