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616-91-1 - N-Acetyl-L-cysteine, 98+% - A15409 - Alfa Aesar

A15409 N-Acetyl-L-cysteine, 98+%

CAS Number
616-91-1
Synonyms

Size Price ($) Quantity Availability
25g 37.68
100g 95.93
500g 380.07
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N-Acetyl-L-cysteine, 98+%

MDL
MFCD00004880
EINECS
210-498-3

Chemical Properties

Formula
C5H9NO3S
Formula Weight
163.20
Melting point
108-111°
Solubility
Soluble in water, ethanol, methanol, dimethyl sulfoxide, hot isopropyl alcohol, methyl acetate and ethyl acetate. Insoluble in chloroform and ether.

Applications

A mucolytic agent for isolation of mycobacteria from sputum.N-Acetyl-L-cysteine is used in the liquefaction and decontamination of sputum during the preparation for recovery of mycobacterium, which is called as Petroff's method. It shows antiviral activity against the influenza A viruses. It is used in the treatment of interstitial lung disease to prevent disease progression. It is an antioxidant, dietary supplement and protects liver. Further, it forms complexes with palladium, thereby it dissolves in water and remove palladium from drugs. Further, it is used in the treatment of paracetamol overdose. In addition to this, it is involved in the treatment of autism, Alzheimer's disease, bipolar disorder, major depressive disorder, obsessive-compulsive disorder, schizophrenia, and specific drug addictions like cocaine and cannabis.

Notes

Store in a cool place. Incompatible with heavy metals, heavy metal salts, rubber, oxygen and strong oxidizing agents.

Literature References

Catalyzes the addition of ammonia to nitriles to form amidines in high yield: Tetrahedron Lett., 40, 7067 (1999).

Sun, Y.; Qi, Z.; He, Q.; Cui, D.; Qian, S.; Ji, L.; Ding, S. The effect of treadmill training and N-acetyl-l-cysteine intervention on biogenesis of cytochrome c oxidase (COX). Free Radical Biol. Med. 2015, 87, 326-335.

Pereira, S.; Shah, A.; Fantus, I. G.; Joseph, J. W.; Giacca, A. Effect of N-acetyl-l-cysteine on insulin resistance caused by prolonged free fatty acid elevation. J. Endocrinol. 2015, 225 (1), 1-7.

Other References

Merck
14,88
Beilstein
1724426
Harmonized Tariff Code
2930.90
TSCA
Yes
RTECS
HA1660000

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