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A15486 4-Fluorobenzylamine, 98+%

CAS Number
140-75-0
Synonyms

Stock No. Size Price ($) Quantity Availability
A15486-09 10g 30.40
A15486-18 50g 100.00
A15486-30 250g 464.00
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4-Fluorobenzylamine, 98+%

MDL
MFCD00008120
EINECS
205-430-4

Chemical Properties

Formula
C7H8FN
Formula Weight
125.15
Boiling Point
182-183°
Flash Point
66°(150°F)
Density
1.095
Refractive Index
1.5130
Storage & Sensitivity
Air Sensitive. Ambient temperatures.
Solubility
Soluble in water.

Applications

4-Fluorobenzylamine is used as a potassium channel blocking agent. It is used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands. It reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate2. It is an important building block for the synthesis of 18F-labeled compounds.

Notes

Air sensitive. Store under inert gas. Incompatible with oxidizing agent, air, carbon dioxide.

Literature References

Walkiria Schlindwein; Emma Waltham; John Burgess; Norman Binsted; Ana Nunes; Andreia Leite; Maria Rangel. New lipophilic 3-hydroxy-4-pyridinonate iron(III) complexes: synthesis and EXAFS structural characterisation. Dalton Transactions. 2006, 10, 1313-1321.

Jenilee Way; Frank Wuest. Fully automated synthesis of 4-[18F]fluorobenzylamine based on borohydride/NiCl2reduction. Nuclear Medicine and Biology. 2013, 40 (3), 411-416.

GHS Hazard and Precautionary Statements

Hazard Statements: H227-H314-H335

Combustible liquid. Causes severe skin burns and eye damage. May cause respiratory irritation.

Precautionary Statements: P210-P235-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
636501
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2921.49
TSCA
Yes

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