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772-79-2 - 4-Chlorophenyl phosphorodichloridate, 98+% - 4-Chlorophenyl dichlorophosphate - A15507 - Alfa Aesar

A15507 4-Chlorophenyl phosphorodichloridate, 98+%

CAS Number
772-79-2
Synonyms
4-Chlorophenyl dichlorophosphate

Size Price ($) Quantity Availability
5g 19.26
25g 72.51
100g 216.90
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4-Chlorophenyl phosphorodichloridate, 98+%

MDL
MFCD00009705
EINECS
212-254-1

Chemical Properties

Formula
C6H4Cl3O2P
Formula Weight
245.43
Boiling Point
113-115°/0.9mm
Flash Point
106°(222°F)
Density
1.508
Refractive Index
1.5398
Sensitivity
Moisture Sensitive
Solubility
Reacts with water.

Applications

4-Chlorophenyl phosphorodichloridate is used as phosphorylation agent. Reactant for preparation of antimicrobial agents, antioxidant agents, antitumor agents, nucleotide anti-viral prodrug.

Notes

Moisture sensitive. Store under inert gas. Store away from moisture, oxidizing agents, alcohols, bases.

Literature References

SA Harris; C McGuigan; G Andrei; R Snoeck; E De Clercq; J Balzarini. Synthesis and Antiviral Evaluation of Phosphoramidate Derivatives of (E)-5-(2-Bromovinyl)-2?-Deoxyuridine. Antivir Chem Chemother. 2001, 12 (5), 293-300.

Honghua CAO; Kentaro Tanaka; Mitsuhiko Shionoya. An Alternative Base-Pairing of Catechol-Bearing Nucleosides by Borate Formation. Chemical and Pharmaceutical Bulletin. 2000, 48 (11), 1745-1748.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Precautionary Statements: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
910754
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2919.90
TSCA
No

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