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A15534 Pyrimidine, 98+%

CAS Number
289-95-2
Synonyms

Stock No. Size Price ($) Quantity Availability
A15534-03 1g 31.60
A15534-06 5g 96.50
A15534-14 25g 365.00
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Pyrimidine, 98+%

MDL
MFCD00006059
EINECS
206-026-0

Chemical Properties

Formula
C4H4N2
Formula Weight
80.09
Melting point
20-22°
Boiling Point
123-124°
Flash Point
31°(87°F)
Density
1.016
Refractive Index
1.5040
Storage & Sensitivity
Hygroscopic. Store under Nitrogen. Ambient temperatures.
Solubility
Fully miscible in water.

Applications

Used in the synthesis and discovery of antiviral medication, such as in the case of HIV and HSV. Also used in the synthesis of potent inhibitors of 15-lipoxygenase in the reduction of the release of leukotrienes. And in ithe production of RNA and DNA, proteins and starches, the regulation of enzymes and cell signaling.

Notes

Hygroscopic. Store under inert gas. Store away from oxidizing agents, water/ moisture.

Literature References

Vilhelm A. Bohr; Charles Allen Smith; Diane S. Okumoto; Philip C. Hanawalt. DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell. 1985, 40 (2), 359-369.

R.B. Setlow; W.L. Carrier. Pyrimidine dimers in ultraviolet-irradiated DNA's. Journal of Molecular Biology. 1996, 17 (1), 237-254.

GHS Hazard and Precautionary Statements

Hazard Statements: H226

Flammable liquid and vapour.

Precautionary Statements: P210-P233-P240-P241-P242-P243-P280-P303+P361+P353-P370+P378q-P501c

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,7987
Beilstein
103894
Hazard Class
3
Packing Group
III
Harmonized Tariff Code
2933.59
TSCA
Yes
RTECS
UV6263000

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