Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

A15559 4-Methoxybenzyl alcohol, 98%

CAS Number
105-13-5
Synonyms
p-Anisyl alcohol
4-Methoxyphenylmethanol

Stock No. Size Price ($) Quantity Availability
A15559-22 100g 29.40
A15559-36 500g 103.00
A15559-0E 2500g 428.00
Add to Cart Bulk/Specialty Print Quote View Item

4-Methoxybenzyl alcohol, 98%

MDL
MFCD00004653
EINECS
203-273-6

Chemical Properties

Formula
C8H10O2
Formula Weight
138.17
Melting point
22-25°
Boiling Point
259°
Flash Point
113°(235°F)
Density
1.110
Refractive Index
1.5450
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in water, chloroform, ethyl acetate.

Applications

4-Methoxybenzyl Alcohol is used in the preparation of semiconductors, nanosheets and nanocrystals. Also is used as a reagent for various chemical organic reactions such as in the synthesis of quinolines. It is used as a fragrance and flavorant. It is used to study the photo catalytic oxidation of 4-methoxybenzyl alcohol to p-anisaldehyde.

Notes

Store in a cool, dry conditions in a well sealed container. Incompatible with oxidizing agent, acids, acid chlorides, acid anhydrides.

Literature References

Radek Cibulka; Rudolf Vasold; Burkhard König. Catalytic photooxidation of 4-methoxybenzyl alcohol with a flavin-zinc(II)-cyclen complex. Chemistry: A European Journal. 2004, 10 (24), 6224-6231.

Valeria B Arce; Sonia G Bertolotti; Fernando J V E Oliveira; Claudio Airoldi; Antonio Arques; Lucas Santos-Juanes; Mónica C Gonzalez; Carlos J Cobos; Patricia E Allegretti; Daniel O Mártire. Triplet state of 4-methoxybenzyl alcohol chemisorbed on silica nanoparticles. Photochemical & Photobiological Sciences. 2012, 11, (6), 1032-1040.

Carboxyl protection agent giving the 4-methoxybenzyl (PMB; 4-methoxyphenylmethyl; MPM) ester, e.g. by reaction with the 4-nitrophenyl ester. The group is stable to 0.5N HCl in MeOH which readily cleaves Boc groups, but can be removed by TFA, leaving Cbz-groups unaffected: Austr. J. Chem., 21, 2543 (1968). For cleavage using AcOH at 90o, see: Synth. Commun., 24, 1151 (1994). For cleavage with Cerium(III)­ chloride heptahydrate, A12947, in the presence of NaI, see: J. Org. Chem., 64, 5696 (1999). See Appendix 6.

Has also been used, in the presence of TFA, to protect thiols: Tetrahedron Lett., 35, 1631 (1994). Cleavage is by refluxing with TFA: Bull. Chem. Soc. Jpn., 37, 433 (1964); Bioorg. Chem. Med. Lett., 3, 739 (1993), or Hg(II) salts: Chem. Pharm. Bull., 26, 1576 (1978); J. Med. Chem., 31, 2199 (1988); J. Org. Chem., 52, 4420 (1987).

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H317-H318

Causes skin irritation. May cause an allergic skin reaction. Causes serious eye damage.

Precautionary Statements: P261-P264b-P272-P280-P302+P352-P305+P351+P338-P310-P333+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. If skin irritation or rash occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,604
Beilstein
636654
Harmonized Tariff Code
2909.49
TSCA
Yes
RTECS
DO8925000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware