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p-Toluoyl chloride was used to prepare antigen, Tolyl-amido-human serum albumin. It is used as a reagent to synthesize (+)-Yashabushitriol, derivatives of Desloratadine.
M H Karol; Y Alarie. Kaputsky. Antigens which detect IgE antibodies in workers sensitive to toluene diisocyanate. Clinical allergy. 1980,10 (1), 101-109.
Shainaz M Landge; M Chidambaram; A.P Singh. Benzoylation of toluene with p-toluoyl chloride over triflic acid functionalized mesoporous Zr-TMS catalyst. Journal of Molecular Catalysis A: Chemical 2004, 213 (2), 257-266.
Hazard Statements: H227-H314-H318
Combustible liquid. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P260-P201-P280-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.