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874-60-2 - p-Toluoyl chloride, 99% - 4-Methylbenzoyl chloride - A15581 - Alfa Aesar

A15581 p-Toluoyl chloride, 99%

CAS Number
874-60-2
Synonyms
4-Methylbenzoyl chloride

Size Price ($) Quantity Availability
100g 22.14
500g 71.12
2500g 304.00
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p-Toluoyl chloride, 99%

MDL
MFCD00000696
EINECS
212-864-8

Chemical Properties

Formula
C8H7ClO
Formula Weight
154.60
Melting point
-2°
Boiling Point
225-227°
Flash Point
82°(179°F)
Density
1.169
Refractive Index
1.5530
Sensitivity
Moisture Sensitive
Solubility
Reacts with water alcohol.

Applications

p-Toluoyl chloride was used to prepare antigen, Tolyl-amido-human serum albumin. It is used as a reagent to synthesize (+)-Yashabushitriol, derivatives of Desloratadine.

Notes

Store at room temperature. Incompatible with oxidizing agent, acids, bases, active metals, alcohols, amines.

Literature References

M H Karol; Y Alarie. Kaputsky. Antigens which detect IgE antibodies in workers sensitive to toluene diisocyanate. Clinical allergy. 1980,10 (1), 101-109.

Shainaz M Landge; M Chidambaram; A.P Singh. Benzoylation of toluene with p-toluoyl chloride over triflic acid functionalized mesoporous Zr-TMS catalyst. Journal of Molecular Catalysis A: Chemical 2004, 213 (2), 257-266.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318-H227

Causes severe skin burns and eye damage. Causes serious eye damage. Combustible liquid.

Precautionary Statements: P280-P305+P351+P338-P309-P310

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician.

Other References

Beilstein
471492
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2916.39
TSCA
Yes
RTECS
XV1660000

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