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It is employed as a catalyst in the synthesis of fluorazone derivatives by one-pot pyrrolation/cyclization of anthranilic acids.
Francesca Aiello, et al. Convenient synthesis of fluorazone derivatives by one-pot pyrrolation/cyclization of anthranilic acids.Tetrahedron Lett.,2011,52(44), 5824-5826.
Ghislaine Priem, et al. A simple and effective synthetic approach to chiral 4-pyridinyl proline derivatives.Tetrahedron Lett.,2002,43(34), 6001-6003.
For a study of regioselective metallation reactions, see: Heterocycles, 35, 151 (1993).
Hazard Statements: H302-H319
Harmful if swallowed. Causes serious eye irritation.
Precautionary Statements: P280f-P305+P351+P338
Wear protective clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.