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51135-96-7 - 4-Benzyl-4-hydroxypiperidine, 97% - 4-Benzyl-4-piperidinol - A15664 - Alfa Aesar

A15664 4-Benzyl-4-hydroxypiperidine, 97%

CAS Number
51135-96-7
Synonyms
4-Benzyl-4-piperidinol

Size Price ($) Quantity Availability
1g 50.88
5g 165.83
25g 510.40
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4-Benzyl-4-hydroxypiperidine, 97%

MDL
MFCD00023147
EINECS
257-003-7

Chemical Properties

Formula
C12H17NO
Formula Weight
191.27
Melting point
ca 80°
Sensitivity
Hygroscopic
Solubility
Slightly soluble in water.

Applications

It is a building block used for the synthesis of various compounds, having therapeutic properties, such as synthesis of 4-Benzimidazolyl-piperidinylcarbonyl-piperidine analogs as histamine H3 antagonists.

Notes

Hygroscopic. Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Laura C. Cooper, et al. 2-Aryl Indole NK1 receptor antagonists: optimisation of indole substitution.Bioorg. Med. Chem. Lett.,2009,11(9), 1233-1236.

Duncan Shawa, et al. 2-Aryl indole NK1 antagonists: optimisation of the amide substituent.Bioorg. Med. Chem. Lett.,2001,11(23), 3031-3034.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1451803
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
TN6836000

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