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A15676 4-Hydroxy-3,5-dimethoxycinnamic acid, 98%

CAS Number
530-59-6
Synonyms
Sinapinic acid
3,5-Dimethoxy-4-hydroxycinnamic acid

Stock No. Size Price ($) Quantity Availability
A15676-03 1g 26.70
A15676-06 5g 78.90
A15676-14 25g 293.00
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4-Hydroxy-3,5-dimethoxycinnamic acid, 98%

MDL
MFCD00004401
EINECS
208-487-3

Chemical Properties

Formula
C11H12O5
Formula Weight
224.21
Melting point
ca 195° dec.
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in methanol, ethanol and dimethyl sulfoxide.

Applications

4-Hydroxy-3,5-dimethoxycinnamic acid is a commonly used matrix in MALDI mass spectrometry. It is a useful matrix for a wide variety of peptides and proteins. It serves well as a matrix for MALDI due to its ability to absorb laser radiation and to also donate protons (H+) to the analyte of interest.

Notes

Store in cool dry place in tightly closed container. With good ventilation. Store away from oxidizing agent.

Literature References

Ronald C. Beavis; and Brian T. Chait. Matrix-assisted laser-desorption mass spectrometry using 355 nm radiation. Rapid Communications in Mass Spectrometry. 1989, 3 (12), 436-439.

Ronald C. Beavis; and Brian T. Chait. Cinnamic acid derivatives as matrices for ultraviolet laser desorption mass spectrometry of proteins. Rapid Communications in Mass Spectrometry. 1989, 3 (12), 432-435.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
2130006
Harmonized Tariff Code
2918.99
TSCA
No

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