Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

501-53-1 - Benzyl chloroformate, 95%, stab. with ca 0.1% sodium carbonate - Carbobenzoxy chloride - Chloroformic acid benzyl ester - A15682 - Alfa Aesar

A15682 Benzyl chloroformate, 95%, stab. with ca 0.1% sodium carbonate

CAS Number
501-53-1
Synonyms
Carbobenzoxy chloride
Chloroformic acid benzyl ester

Size Price ($) Quantity Availability
50g 38.52
250g 148.50
1000g 465.60
Add to Cart Add to Quote Request View Item

Benzyl chloroformate, 95%, stab. with ca 0.1% sodium carbonate

MDL
MFCD00000640
EINECS
207-925-0

Chemical Properties

Formula
C8H7ClO2
Formula Weight
170.60
Melting point
-20°
Boiling Point
178-180°
Flash Point
125°(257°F)
Density
1.195
Refractive Index
1.5170
Sensitivity
Moisture Sensitive
Solubility
Miscible with ether, acetone and benzene.

Applications

Benzyl chloroformate is widely used as a reactive chemical intermediate in plastic, pharmaceutical, agricultural and organic chemicals. It is useful for the introduction of carboxybenzyl (cbz) protecting group for amines such as aniline in organic synthesis. It is also involved in the synthesis of 1,2,4-oxadiazoles.

Notes

Store in cool place. Moisture sensitive.

Literature References

Kim, J. S.; Kang, J. C.; Yoo, G. H.; Jin, X.; Myeong, I. S.; Oh, C. Y.; Ham, W. H. Stereoselective total synthesis of (-)-conduramine F-1 via chiral 1,3-oxazine. Tetrahedron 2015, 71 (18), 2772-2776.

Lezama, J.; Domínguez, R. M.; Chuchani, G. Kinetics of the Gas-Phase Elimination Reaction of Benzyl Chloroformate and Neopentyl Chloroformate. Int. J. Chem. Kinet. 2015, 47 (2), 104-112.

GHS Hazard and Precautionary Statements

Hazard Statements: H314-H318-H400-H410

Causes severe skin burns and eye damage. Causes serious eye damage. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.

Precautionary Statements: P273-P280-P305+P351+P338-P309-P310-P501a

Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or if you feel unwell: Immediately call a POISON CENTER or doctor/physician. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1801
Hazard Class
8
Packing Group
I
Harmonized Tariff Code
2915.90
TSCA
Yes

Recommended

  • A14708

    Di-tert-butyl dicarbonate, 97+%
  • A11801

    N-Ethyldiisopropylamine, 99%
  • A13016

    4-(Dimethylamino)pyridine, 99%
  • A12728

    Silicone oil, for oil baths, usable range from -40 to +200°C
  • A12733

    TEMPO, free radical, 98+%

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware