I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
3-Methyl-2-cyclohexen-1-one was used in the synthesis of 19-nor-1α, 25-dihydroxyvitamin D(3) derivatives. It was also used in sex pheromone of the Douglas-fir beetle. Used in nut flavor.
X Zhou; G D Zhu; D Van Haver; M Vandewalle; P J De Clercq; A Verstuyf; R Bouillon. Synthesis, biological activity, and conformational analysis of four seco-D-15,19-bisnor-1alpha,25-dihydroxyvitamin D analogues, diastereomeric at C17 and C20. Journal of Medicinal Chemistry. 1999, 42 (18), 3539-3556.
Donald S. Noyce, Malcolm. Evett. Mechanism of the acid-catalyzed double bond migration in 3-cyclohexen-1-one and 3-methyl-3-cyclohexen-1-one. J. Org. Chem. 1972, 37 (3), 394-397.
For photochemical (2 + 2) photocycloaddition reaction with ethylene, as a general method for synthesis of fused cyclobutane systems, see: Org. Synth. Coll., 7, 315 (1990).
For conversion to the silyl enol ether and stereoselective aldol-type coupling, see: Tetrahedron, 45, 6101 (1989):
Hazard Statements: H227-H302
Combustible liquid. Harmful if swallowed.
Precautionary Statements: P210u-P280a-P264-P301+P312a-P403+P235-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. Wash thoroughly after handling. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Store in a well-ventilated place. Keep cool. Dispose of contents/container in accordance with local/regional/national/international regulations.