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Used for preparing isoxazolyl penicillin derivatives. 4-tert-Butylbenzaldehyde is suitable for use in a kinetic study to evaluate the kinetic constants (KI) for inhibition of mushroom tyrosinase by 4-substituted benzaldehydes. It is also an important intermediate for the synthesis of medicines, dyes, flavor and fragrance compounds.
Pichat. P, et al. Photocatalytic oxidation of liquid (or gaseous) 4-tert-butyltoluene to 4-tert-butylbenzaldehyde by O2 (or air) over TiO2.Nouveau journal de chimie.,1986,10(10), 545-551.
Weihua Yu, et al. Peroxide oxidation of 4-tert-butyltoluene to 4-tert-butylbenzaldehyde over titanium(IV)-functionalized mesostructured silica.Microporous Mesoporous Mater.,2007,104(1-3), 151-158.
Hazard Statements: H317-H335
May cause an allergic skin reaction. May cause respiratory irritation.
Precautionary Statements: P261-P271-P272-P280g-P302+P352-P304+P340-P312-P333+P313-P363-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation or rash occurs: Get medical advice/attention. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant