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A15751 Homopiperazine, 98%

CAS Number
505-66-8
Synonyms
1,4-Diazacycloheptane
Hexahydro-1,4-diazepine

Stock No. Size Price ($) Quantity Availability
A15751-14 25g 91.60
A15751-22 100g 259.00
A15751-36 500g 590.00
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Homopiperazine, 98%

MDL
MFCD00006933
EINECS
208-016-1

Chemical Properties

Formula
C5H12N2
Formula Weight
100.17
Melting point
38-44°
Boiling Point
168-170°
Flash Point
64°(147°F)
Density
0.95
Storage & Sensitivity
Hygroscopic. Air Sensitive. Ambient temperatures.
Solubility
Soluble in water.

Applications

Homopiperazine is used to prepare 1,4-bis-(2-thiazolyl)-1,4-diazacycloheptane by reacting with 2-bromo-thiazole. It acts as an intermediate for repaglinide and fasudil hydrochloride. It is also used in the preparation of potent H3 receptor antagonists, which is used for the treatment of neurodegenerative conditions. Further, it is used in vesicant, cosmetic, emulsifier and energetic material. It acts as a corrosion inhibitor for iron. In pharmaceuticals, it is employed as antipyretic and reducing blood sugar, adiposity, calm, antipsychotic and anti-nervous.

Notes

Hygroscopic. Air sensitive. Incompatible with strong oxidizing agents and strong acids.

Literature References

Keypour, H.; Rezaeivala, M.; Mirzaei-Monsef, M.; Sayin, K.; Dilek, N.; Unver, H. Synthesis and characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes with a new homopiperazine macrocyclic Schiff base ligand. Inorg. Chim. Acta 2015, 432, 243-249.

Vinodh, R.; Bhagiyalakshmi, M.; Hemalatha, P.; Ganesh, M.; Peng, M. M.; Palanichamy, M.; Cha, W. S.; Jang, H. T. Homopiperazine Grafted Mesoporous Silicas from Rice Husk Ash for CO2 Adsorption. J. Nanosci. Nanotechnol. 2014, 14 (6), 4639-4648.

GHS Hazard and Precautionary Statements

Hazard Statements: H312-H314

Harmful in contact with skin. Causes severe skin burns and eye damage.

Precautionary Statements: P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
102711
Hazard Class
8
Packing Group
III
Harmonized Tariff Code
2933.99
TSCA
Yes
RTECS
HM3850000

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