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Used as pharmaceutical intermediate.
Domenico Spinelli .; Paolo Zanirato.; Elvira Di Miceli.; Liliana Lamartina.;Francesco Guerrera. On the Reaction of 3-Bromo-2-nitrobenzo[b]thiophene 13C-Labeled at C-2 with 3-(Trifluoromethyl)aniline:? A Preliminary Insight into a Nucleophilic Substitution with Rearrangement. J. Org. Chem. 1997, 62 (15), 4921-4923 .
V. Arjunan.; T. Rani.; S. Mohan. Spectroscopic and quantum chemical electronic structure investigations of 2-(trifluoromethyl)aniline and 3-(trifluoromethyl)aniline.J. Mol. Struct. 2011, (1-3), 179-193 .
Used in an example of a general method for the conversion of aromatic amines to sulfonyl chlorides by reaction of the diazonium chlorides with SO2: Org. Synth. Coll., 7, 508 (1990).
Hazard Statements: H227-H302+H312-H315-H318-H330-H335-H373
Combustible liquid. Harmful if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye damage. Fatal if inhaled. May cause respiratory irritation. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P210-P235-P260-P264b-P270-P271-P280-P284-P301+P312-P302+P352-P304+P340-P305+P351+P338-P310-P312-P314-P330-P332+P313-P362-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep cool. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. Wear respiratory protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Get medical advice/attention if you feel unwell. Rinse mouth. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant