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4-Benzyloxybenzaldehyde is used in the synthesis of (5-fluoro-(2R*,3S*)-2,3-bis(4-hydroxyphenyl)pentanenitrile),an estrogen receptor β-selective ligand. It is a position isomer of the adenylyl cyclase activator 2-benzyloxybenzaldehyde.
Jeongsoo Yoo.; Carmen S Dence.; Terry L Sharp.; John A Katzenellenbogen.; Michael J Welch. Synthesis of an estrogen receptor beta-selective radioligand: 5-[18F]fluoro-(2R,3S)-2,3-bis(4-hydroxyphenyl)pentanenitrile and comparison of in vivo distribution with 16alpha-[18F]fluoro-17beta-estradiol. Journal of Medicinal Chemistry. 2005, 48 (20), 6366-6378.
Jonathan S. Lindsey.; Henry C. Hsu.; Irwin C. Schreiman. Synthesis of tetraphenylporphyrins under very mild conditions. Tetrahedron Letters. 1986, 27 (41), 4969-4970.