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Ethyl isodehydroacetate is used in the synthesis of bidentate ligands. Also used in the preparation of insect growth regulators with juvenile hormone activity. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals and agrochemicals.
Richard H. Wiley.; H. G. Ellert. 2-Pyrones. XXVI. Alkylidene Methylglutaconic Acids and 3,6-Dialkyl-5-carboxy-5,6-dihydro-2-pyrones from Methyl β-Methylglutaconate and Ethyl Isodehydroacetate and their Isomerization and Decarboxylation. J. Am. Chem. Soc. 1957, 79 (9), 2266-2271 .
YOSHIHIRO NITTA.; YASUSHI ARAKAWA. Reaction of Ethyl Acetoacetate with p-Toluenesulfonic Acid : Formation of Ethyl Isodehydroacetate and/or Ethyl p-Toluenesulfonate. Chemical and Pharmaceutical Bulletin. 1983, 31 (4), 1385-1388.