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86-98-6 - 4,7-Dichloroquinoline, 98% - A15985 - Alfa Aesar

A15985 4,7-Dichloroquinoline, 98%

CAS Number
86-98-6
Synonyms

Size Price ($) Quantity Availability
25g 31.75
100g 92.08
500g 305.60
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4,7-Dichloroquinoline, 98%

MDL
MFCD00006774
EINECS
201-714-7

Chemical Properties

Formula
C9H5Cl2N
Formula Weight
198.05
Melting point
83-87°
Boiling Point
148°/10mm
Flash Point
164°(327°F)
Solubility
Insoluble in water.

Applications

4,7-Dichloroquinoline is used as a drug chloroquine phosphate intermediate. It is also is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti-microbial agents showing efficacy against common bacterial strains.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Alexander R. Surrey.; Royal A. Cutler. The Role of Phenol in the Reaction of 4,7-Dichloroquinoline with Novol Diamine. J. Am. Chem. Soc. 1951, 73 (6), 2623-2626.

Robert C. Elderfield.; Walter J. Gensler.; Oskar Birstein.; Frank J. Kreysa.; John T. Maynard.; Jean Galbreath. Synthesis of Certain Simple 4-Aminoquinoline Derivatives. J. Am. Chem. Soc. 1946, 68 (7), 1250-1251.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
125359
Harmonized Tariff Code
2933.49
TSCA
Yes
RTECS
VB4200000

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