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A15985 4,7-Dichloroquinoline, 98%

CAS Number
86-98-6
Synonyms

Stock No. Size Price ($) Quantity Availability
A15985-14 25g 34.50
A15985-22 100g 93.50
A15985-36 500g 359.00
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4,7-Dichloroquinoline, 98%

MDL
MFCD00006774
EINECS
201-714-7

Chemical Properties

Formula
C9H5Cl2N
Formula Weight
198.05
Melting point
83-87°
Boiling Point
148°/10mm
Flash Point
164°(327°F)
Storage & Sensitivity
Ambient temperatures.
Solubility
Insoluble in water.

Applications

4,7-Dichloroquinoline is used as a drug chloroquine phosphate intermediate. It is also is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti-microbial agents showing efficacy against common bacterial strains.

Notes

Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.

Literature References

Alexander R. Surrey.; Royal A. Cutler. The Role of Phenol in the Reaction of 4,7-Dichloroquinoline with Novol Diamine. J. Am. Chem. Soc. 1951, 73 (6), 2623-2626.

Robert C. Elderfield.; Walter J. Gensler.; Oskar Birstein.; Frank J. Kreysa.; John T. Maynard.; Jean Galbreath. Synthesis of Certain Simple 4-Aminoquinoline Derivatives. J. Am. Chem. Soc. 1946, 68 (7), 1250-1251.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
125359
Harmonized Tariff Code
2933.49
TSCA
Yes
RTECS
VB4200000

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