2,6-Difluorophenol undergoes oxidative polymerization in the presence of the Fe-N,N?-bis(salicylidene)ethylenediamine (salen) complex (catalyst) and hydrogen peroxide (oxidizing agent) to give poly(2,6-difluoro-1,4-phenylene oxide). It is also used as pharmaceutical intermediates.
Ryohei Ikeda; Hozumi Tanaka; Hiroshi Uyama; Shiro Kobayashi. Oxidative polymerization of 2,6-difluorophenol to crystalline poly(2,6-difluoro-1,4-phenylene oxide). Macromolecules. 2000, 33, (18),6648-6652
Jian Qiu; Scott H.Stevenson; Michael J.O'Beirne; Richard B.Silverman . 2,6-Difluorophenol as a bioisostere of a carboxylic acid:? Bioisosteric analogues of γ-aminobutyric acid. J. Med. Chem. 1999, 42, (2),329-332
Hazard Statements: H228-H301-H311-H314-H318
Flammable solid. Toxic if swallowed. Toxic in contact with skin. Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statements: P210-P301+P310a-P303+P361+P353-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. IF SWALLOWED: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.