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Sodium hydroxide is widely used in variety of large scale applications such as pulp and paper manufacturing, in the production of soap and detergents as well as water treatment. It finds application in the base- driven hydrolysis of esters, amides and alkyl halides. It is also used as an industrial cleaning agent, an additive in drilling mud to increase alkalinity in bentonite in petroleum industry and as a powerful degreaser on stainless steel and glass bakeware. It is utilized in the Maxam-Gilbert DNA sequencing technique, chocolate and cocoa processing, soft drink processing, caramel coloring production and for thickening ice cream. It is often used to neutralize acids and prepare sodium salts of reagents. It forms a solution with sodium dodecyl sulfate and plays an important role for the decontamination of mycobacteria.
Michalska, K.; Bizukojc, M.; Ledakowicz, S. Pretreatment of energy crops with sodium hydroxide and cellulolytic enzymes to increase biogas production. Biomass Bioenergy 2015, 80, 213-221.
Zhu, Q. L.; Tsumori, N.; Xu, Q. Sodium hydroxide-assisted growth of uniform Pd nanoparticles on nanoporous carbon MSC-30 for efficient and complete dehydrogenation of formic acid under ambient conditions. Chem. Sci. 2014, 5 (1), 195-199.
Hazard Statements: H314-H335
Causes severe skin burns and eye damage. May cause respiratory irritation.
Precautionary Statements: P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant