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Acetamidine hydrochloride was used in the preparation of decarboxyectoine. It was also used in the synthesis of ethyl 4-(4-hydroxyphenyl)methylidene-2-methyl-5-oxo-1-imidazolacetate.
Michael Schnoor; Peter Voss; Paul Cullen; Thomas Boking; Hans-Joachim Galla; Erwin A.Galinski; Stefan Lorkowski. Characterization of the synthetic compatible solute homoectoine as a potent PCR enhancer. Biochemical and Biophysical Research Communications. 2004, 322, (3),867-872
H.Niwa; S.Inouye; T Hirano; T.Matsuno; S.Kojima; M.Kubota; M.Ohashi; F.I.Tsuji. Chemical nature of the light emitter of the Aequorea green fluorescent protein. PNAS. 1996, 93, (24),13617-13622
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c
Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant