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145224-94-8 - MES monohydrate, 98% - 4-Morpholineethanesulfonic acid monohydrate - 2-(4-Morpholinyl)ethanesulfonic acid monohydrate - A16104 - Alfa Aesar

A16104 MES monohydrate, 98%

CAS Number
145224-94-8
Synonyms
4-Morpholineethanesulfonic acid monohydrate
2-(4-Morpholinyl)ethanesulfonic acid monohydrate

Size Price ($) Quantity Availability
25g 31.93
100g 75.01
500g 316.16
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MES monohydrate, 98%

MDL
MFCD00149409
EINECS
224-632-3

Chemical Properties

Formula
C6H13NO4S•H2O
Formula Weight
213.26 (195.24anhy)
Melting point
ca 308° dec.
Solubility
Soluble in water.

Applications

MES monohydrate is a biological buffer often referred to as Good’s buffer. It is useful for cell culture media and protein based buffer formulations to maintain a stable environment in solution. It is also used in the purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors. It is a useful resolving agent for very small proteins on bis-tris gels. Buffer solutions are used as a means of keeping pH at a nearly constant value in a wide variety of chemical applications.

Notes

Incompatible with strong oxidizing agents.

Literature References

Biological buffer, pKa = 6.15 at 20o: Biochemistry, 5, 467 (1966).

Rahman, R. N. Z. R. A.; Masomian, M.; Leow, A. T. C.; Ali, M. S. M. Influence of protein solution in nucleation and optimized formulation for the growth of ARM lipase crystal. J. Cryst. Growth 2015, 426, 234-242.

Baumann, P.; Baumgartner, K.; Hubbuch, J. Influence of binding pH and protein solubility on the dynamic binding capacity in hydrophobic interaction chromatography. J. Chromatogr. A 2015, 1396, 77-85.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,5902
Beilstein
141319
Harmonized Tariff Code
2934.99
TSCA
Yes
RTECS
QE3479500

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