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Propionaldehyde applications include as an intermediate, in pharmaceuticals, perfumes, plastics and polyols or polyhydric alcohols. It is also used as a precursor to trimethylolethane (CH3C(CH2OH)3) through a condensation reaction with formaldehyde, this triol is an important intermediate in the production of alkyd resins. Other applications include reduction to propanol and oxidation to propionic acid. Also used in PEGylated protein purification.
Norihiko Takeda; Tsukasa Torimoto; Srinivasan Sampath; Susumu Kuwabata; Hiroshi Yoneyama. Effect of inert supports for titanium dioxide loading on enhancement of photodecomposition rate of gaseous propionaldehyde. J. Phys. Chem. 1995, 99, (24),9986-9991
A.Ueno; H.Suzuki; Y.Kotera. Particle-size distribution of nickel dispersed on silica and its effects on hydrogenation of propionaldehyde. J. Chem. Soc., Faraday Trans. 1. 1983, 79, (1),127-136
Hazard Statements: H225-H302-H315-H318-H332-H335
Highly flammable liquid and vapour. Harmful if swallowed. Causes skin irritation. Causes serious eye damage. Harmful if inhaled. May cause respiratory irritation.
Precautionary Statements: P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P363-P370+P378q-P501c
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant