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Source of the 3-carboxypropyl side chain in Friedel-Crafts alkylations: J. Am. Chem. Soc., 74, 4721 (1952); Org. Synth. Coll., 4, 898 (1963).
ɑ-Bromination, and dehydrobromination gives the butenolide: Org. Synth. Coll., 5, 255 (1973). The ɑ-dibromo-compound is a useful precursor of arylazetidines: Tetrahedron, 45, 629 (1989):
Hazard Statements: H302-H315-H318
Harmful if swallowed. Causes skin irritation. Causes serious eye damage.
Precautionary Statements: P280a-P305+P351+P338-P310a-P301+P312a-P321-P501a
Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Specific treatment (see label). Dispose of contents/container in accordance with local/regional/national/international regulations.