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Potassium acetate is used as deicer to remove snow and ice from the surface and considered as a replacement for calcium chloride or magnesium chloride. It is used as a food additive, as a buffer in biological research, as an extinguishing agent used in class K fire extinguishers and as a catalyst to produce polyurethane polymers. It is utilized for the precipitation of dodecyl sulfate bound proteins, thereby removal of proteins from DNA. It plays an important role in preserving tissues, fixation and mummification.
Has been found to give faster reaction than sodium acetate in the Perkin condensation of carboxylic acid anhydrides with aromatic aldehydes: Org. Synth. Coll., 3, 127, 426 (1955); review: Org. React., 1, 210 (1942).
The nucleophilicity of acetate anion, e.g. in benzene or acetonitrile, is greatly increased in the presence of 18-crown-6: Tetrahedron Lett., 2417 (1974). In a comparative study of various anions in acetonitrile, 'naked' acetate, formed in this manner, was surprisingly found to be the most nucleophilic: Tetrahedron Lett., 4205 (1975).
Kathiravan, S.; Nicholls, I. A. Palladium Catalyzed Vinyltrifluoromethylation of Aryl Halides through Decarboxylative Cross-Coupling with 2-(Trifluoromethyl) acrylic Acid. Org. Lett. 2015, 17 (8), 1874-1877.
Rodríguez-Palmeiro, I.; Rodríguez-Escontrela, I.; Rodríguez, O.; Arce, A.; Soto, A. Characterization and interfacial properties of the surfactant ionic liquid 1-dodecyl-3-methyl imidazolium acetate for enhanced oil recovery. RSC Adv. 2015, 5 (47), 37392-37398.
Hazard Statements: H500
May form combustible dust concentrations in air