I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.
2-Aminoethyl diphenylborinate is used for the densitometric determination of flavonoids and TRP activator. It is also used to manipulate intracellular release of calcium ions and in preparation of apoptotic inducers. It serves as a reactant for preparation of apoptotic inducers and in membrane-permeable SOCE (store operated calcuym entry) inhibitor.
Reagent for densitometric determination of flavonoids: J. Chromat., 351, 351 (1986); 437, 260 (1988)./n
Ozaki, S.; Suzuki, A. Z.; Bauer, P. O.; Ebisui, E.; Mikoshiba, K. 2-Aminoethyl diphenylborinate (2-APB) analogues: Regulation of Ca2+ signaling. Biochem. Biophys. Res. Commun. 2013, 441 (2), 286-290.
Hofer, A.; Kovacs, G.; Zappatini, A.; Leuenberger, M.; Hediger, M. A.; Lochner, M. Design, synthesis and pharmacological characterization of analogs of 2-aminoethyl diphenylborinate (2-APB), a known store-operated calcium channel blocker, for inhibition of TRPV6-mediated calcium transport. Bioinorg. Med. Chem. 2013, 21 (11), 3202-3213.
Yildar, M.; Aksit, H.; Korkut, O.; Ozyigit, M. O.; Sunay, B.; Seyrek, K. Protective effect of 2-aminoethyl diphenylborinate on acute ischemia-reperfusion injury in the rat kidney. J. Surg. Res. 2014, 187 (2), 683-689.
Mossaad, E.; Furuyam, W.; Enomoto,M.; Kawai, S.; Mikoshibaf, K.; Kawazu, S. Simultaneous Administration of 2-Aminoethyl Diphenylborinate and Chloroquine Reverses Chloroquine Resistance in Malaria Parasites. Antimicrob. Agents Chemother. 2015,59 (5), 2890-2892.
Agatonovic-Kustrin, S.; Hettiarachchi, C. G.; Morton, D. W.; Razic, S. Analysis of phenolics in wine by high performance thin-layer chromatography with gradient elution and high resolution plate imaging. J. Pharm. Biomed. Anal. 2015, 102, 93-99.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.