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Hydrogen chloride, 4M in 1,4-dioxane is used in the preparation of N-methyl-O-benzoylhydroxylamine hydrochloride via reaction with benzoic acid, carbonyldiimidazole and N-methylhydroxylamine hydrochloride.
Ito, S.; Takahashi, K.; Nozaki, K. Formal Aryne Polymerization: Use of [2.2. 1] Oxabicyclic Alkenes as Aryne Equivalents. J. Am. Chem. Soc. 2014, 136 (21), 7547-7550..
Kato, E.; Tsuji, H.; Kawabata, J. Selective purification of intestinal maltase complex by affinity chromatography employing an uncompetitive inhibitor as the ligand. Tetrahedron 2015, 71 (9), 1419-1424.
Hazard Statements: H225-H314-H331-H335-H350
Highly flammable liquid and vapour. Causes severe skin burns and eye damage. Toxic if inhaled. May cause respiratory irritation. May cause cancer.
Precautionary Statements: P201-P202-P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P281-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep container tightly closed. Keep cool. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. Use only non-sparking tools. Take precautionary measures against static discharge. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. In case of fire: Use CO2, dry chemical, or foam Dispose of contents/ container to an approved waste disposal plant