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A16942 5-Aminolevulinic acid hydrochloride, 99%

CAS Number
5451-09-2
Synonyms
5-Amino-4-ketovaleric acid hydrochloride

Stock No. Size Price ($) Quantity Availability
A16942-ME 500mg 73.10
A16942-04 2g 208.00
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5-Aminolevulinic acid hydrochloride, 99%

MDL
MFCD00012869
EINECS
226-679-5

Chemical Properties

Formula
C5H9NO3•HCl
Formula Weight
167.59
Melting point
ca 156° dec.
Storage & Sensitivity
Store under Nitrogen. Keep Cold. Hygroscopic.
Solubility
Soluble in dimethyl sulfoxide, methanol and water.

Applications

5-Aminolevulinic acid hydrochloride finds an important role as a precursor in the synthesis of tetrapyrroles such as chlorophyll and heme. It is widely utilized in photodynamic therapy of diseases namely, Paget’s disease and human papillomavirus (HPV) infection-associated cervical condylomata acuminata.

Notes

Store in a cool place.

Literature References

Yang, X.; Li, W.; Palasuberniam, P.; Myers, K. A.; Wang, C.; Chen, B. Effects of Silencing Heme Biosynthesis Enzymes on 5-Aminolevulinic Acid-mediated Protoporphyrin IX Fluorescence and Photodynamic Therapy. Photochem. Photobiol. 2015, 91 (4), 923-930.

Nunkaew, T.; Kantachote, D.; Nitoda, T.; Kanzaki, H. Selection of salt tolerant purple nonsulfur bacteria producing 5-aminolevulinic acid (ALA) and reducing methane emissions from microbial rice straw degradation. Appl. Soil Ecol. 2015, 86, 113-120.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,446
Beilstein
3690651
Harmonized Tariff Code
2922.49
TSCA
No
RTECS
OI1640000

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