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Sodium trichloroacetate, is used in acid binding reagent in the textile industry in the dying process. Sodium trichloroacetate has been reported previously to be an effective denaturation reagent for proteins was applied to poly(l-lysine) and poly(l-glutamic acid) to see its effects on a coil-to-helix transition and on the chemical reactivities of the ε-amino group of poly(l-lysine). Addition of sodium trichloroacetate to poly-(l-lysine) induced a helical conformation even at neutral pH where the ε-amino group of the polymer was protonated.
MG Murray. Use of sodium trichloroacetate and mung bean nuclease to increase sensitivity and precision during transcript mapping. Analytical biochemistry. 1986158 (1), 165-170.
AJ Loustalot.; R Ferrer. Studies on the persistence and movement of sodium trichloroacetate in the soil. Agron. J. 19505 (3), 323-325.
Dichlorocarbene precursor by thermolysis: Rec. Trav. Chim., 80, 740 (1961); J. Org. Chem., 29, 1113 (1964), or low temperature reaction using BTEAC in the absence of solvent: Tetrahedron Lett., 91 (1976).
For preparation of phenyl trichloromethyl mercury by addition of dichlorocarbene to phenylmercuric chloride, see: Org. Synth. Coll., 5, 969 (1973).
Hazard Statements: H335
May cause respiratory irritation.
Precautionary Statements: P261-P304+P340-P312a-P405-P403+P233-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.