5-Hydroxy-1-tetralone, is used as a metabolite of Levobunolol (L335000) and d-Bunolol (L335010). It is also used as a reagent for the determination of hexoses and oligosaccharides by a fluorescence technique. A reagent that is used for fluorescence determination of enzyme activity. Some of the other applications include as internal standard during HPLC determination of 4-hydroxymephenytoin (4-OH-M) in human urine, as fluorescent labeling reagent during micro detection of glycosphingolipid on TLC plates, in synthesis of 1,2,3,4-tetrahydro-5H-1-benzazepine-quinone derivatives, in synthesis of new chiral oxathiane.
T Momose.; Y Ohkura. Organic analysisXX: Microestimation of blood sugar with 5-Hydroxy-1-tetralone. Talanta. 19593 (2), 151-154.
CF Schwender.; S Farber.; C Blaum. Derivatives of 3, 4-dihydro-1 (2H)-naphthalenone as. beta.-adrenergic blocking agents. 1. Bunolol and related analogs. J. Med. Chem . 197013 (4), 684-688.
Reagent for the determination of hexoses and oligosaccharides by a fluorescence technique: Chem. Abs., 2682h (1957).
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.