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632-69-9 - Rose Bengal - Acid Red 94 - C.I. 45440 - A17053 - Alfa Aesar

A17053 Rose Bengal

CAS Number
632-69-9
Synonyms
Acid Red 94
C.I. 45440

Size Price ($) Quantity Availability
25g 40.56
100g 121.54
500g 471.74
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Rose Bengal

MDL
MFCD00151169
EINECS
211-183-3

Chemical Properties

Formula
C20H2Cl4I4Na2O5
Formula Weight
1017.65
Melting point
>300°
Sensitivity
Light Sensitive
Solubility
Soluble in water.

Applications

Rose Bengal is a stain used in the eye drops to identify the eye damage. It finds application in the preparation of foraminifera for microscopic analysis, photosensitizing reactions and as a dye. In synthetic chemistry, it is utilized to convert triplet oxygen to singlet oxygen, which is used in [2+2] cycloadditions with alkenes. Its derivatives have important medical functions and used for the treatment of cancer. It acts as an alternative to phloxine B in Kreyberg's stain for keratin and mucus. As a fluorescent probe, it is used for the determination of NAD binding sites of alcohol dehydrogenase.

Notes

Incompatible with strong oxidizing agents.

Literature References

Yuan, K.; Wang, J.; Zhai, H.; Chen, Z.; Huang, L.; Su, Z. Sensitive determination of rose bengal in brown sugar by a molecularly imprinted solid-phase extraction monolithic capillary column coupled with capillary electrophoresis. Anal. Methods 2015, 7 (19), 8297-8303.

Lee, J. S.; Lee, B. I.; Park, C. B. Photo-induced inhibition of Alzheimer's beta-amyloid aggregation in vitro by rose bengal. Biomater. 2015, 38, 43-49.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,8262
Beilstein
3645857
Harmonized Tariff Code
3204.12
TSCA
Yes
RTECS
LM5920000

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