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2-Methylimidazole is used as a raw material for the preparation of nitroimidazole antibiotics, which is useful in combat anaerobic bacterial and parasitic infections. It acts as a ligand in coordination chemistry. It is also employed as a hardener or accelerator for epoxy resin and auxiliary agent for textile dyes. Further, it acts as a catalyst for refolding of enhanced colored fluorescent protein. It is also useful as a building block in the synthesis of biologically active compounds. In addition to this, it is used as an active pharmaceutical ingredient intermediate such as metronidazole and dimetridazole.
Xu, X. B.; Liu, D. B.; Yu, S. J.; Yu, P.; Zhao, Z. G. Separation and determination of 4-methylimidazole, 2-methylimidazole and 5-hydroxymethylfurfural in beverages by amino trap column coupled with pulsed amperometric detection. Food Chem. 2015, 169, 224-229.
Wu, X.; Huang, M.; Kong, F.; Yu, S. Short communication: Study on the formation of 2-methylimidazole and 4-methylimidazole in the Maillard reaction. J. Dairy Sci. 2015, 98 (12), 8565-8571.
Hazard Statements: H302-H314-H318-H351
Harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye damage. Suspected of causing cancer.
Precautionary Statements: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.