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298-81-7 - 8-Methoxypsoralen, 99% - Xanthotoxin - A17108 - Alfa Aesar

A17108 8-Methoxypsoralen, 99%

CAS Number
298-81-7
Synonyms
Xanthotoxin

Size Price ($) Quantity Availability
1g 31.93
5g 126.69
25g 440.80
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8-Methoxypsoralen, 99%

MDL
MFCD00005009
EINECS
206-066-9

Chemical Properties

Formula
C12H8O4
Formula Weight
216.20
Melting point
146-150°
Solubility
Soluble in acetone, ethanol (slight), acetic acid, and chloroform (50 mg/ml). Insoluble in water.

Applications

8-Methoxypsoralen, is used in Photochemotherapy (methoxsalen with long wave ultraviolet radiation) is indicated for the repigmentation of idiopathic vitiligo. It is also used in Photopheresis (methoxsalen with long wave ultraviolet radiation of white blood cells) is indicated for use with the UVAR* System in the palliative treatment of the skin manifestations of cutaneous T-cell lymphoma.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Literature References

NJ Lowe.; D Weingarten.; T Bourget, LS Moy. PUVA therapy for psoriasis: comparison of oral and bath-water delivery of 8-methoxypsoralen. Journal of the American Academy of Dermatology. 198614 (5), 754-760.

S Igali.; BA Bridges.; MJ Ashwood-Smith. Mutagenesis in Escherichia coli IV. Photosensitization to near ultraviolet light by 8-methoxypsoralen. Journal of the American Academy of Dermatology. 19709 (1), 21-30.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H317

Harmful if swallowed. May cause an allergic skin reaction.

Precautionary Statements: P261-P280-P264-P270-P301+P312-P363-P321-P333+P313-P302+P352-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. IF ON SKIN: Wash with plenty of soap and water. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,5988
Beilstein
196453
Harmonized Tariff Code
2932.20
TSCA
Yes
RTECS
LV1400000

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