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8-Methoxypsoralen, is used in Photochemotherapy (methoxsalen with long wave ultraviolet radiation) is indicated for the repigmentation of idiopathic vitiligo. It is also used in Photopheresis (methoxsalen with long wave ultraviolet radiation of white blood cells) is indicated for use with the UVAR* System in the palliative treatment of the skin manifestations of cutaneous T-cell lymphoma.
NJ Lowe.; D Weingarten.; T Bourget, LS Moy. PUVA therapy for psoriasis: comparison of oral and bath-water delivery of 8-methoxypsoralen. Journal of the American Academy of Dermatology. 198614 (5), 754-760.
S Igali.; BA Bridges.; MJ Ashwood-Smith. Mutagenesis in Escherichia coli IV. Photosensitization to near ultraviolet light by 8-methoxypsoralen. Journal of the American Academy of Dermatology. 19709 (1), 21-30.
Hazard Statements: H302-H314-H340-H350
Harmful if swallowed. Causes severe skin burns and eye damage. May cause genetic defects. May cause cancer.
Precautionary Statements: P201-P202-P260-P264b-P270-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use personal protective equipment as required. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant