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A17108 8-Methoxypsoralen, 99%

CAS Number
298-81-7
Synonyms
Xanthotoxin

Stock No. Size Price ($) Quantity Availability
A17108-03 1g 32.40
A17108-06 5g 111.00
A17108-14 25g 539.00
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8-Methoxypsoralen, 99%

MDL
MFCD00005009
EINECS
206-066-9

Chemical Properties

Formula
C12H8O4
Formula Weight
216.20
Melting point
146-150°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubility
Soluble in acetone, ethanol (slight), acetic acid, and chloroform (50 mg/ml). Insoluble in water.

Applications

8-Methoxypsoralen, is used in Photochemotherapy (methoxsalen with long wave ultraviolet radiation) is indicated for the repigmentation of idiopathic vitiligo. It is also used in Photopheresis (methoxsalen with long wave ultraviolet radiation of white blood cells) is indicated for use with the UVAR* System in the palliative treatment of the skin manifestations of cutaneous T-cell lymphoma.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Light sensitive. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Literature References

NJ Lowe.; D Weingarten.; T Bourget, LS Moy. PUVA therapy for psoriasis: comparison of oral and bath-water delivery of 8-methoxypsoralen. Journal of the American Academy of Dermatology. 198614 (5), 754-760.

S Igali.; BA Bridges.; MJ Ashwood-Smith. Mutagenesis in Escherichia coli IV. Photosensitization to near ultraviolet light by 8-methoxypsoralen. Journal of the American Academy of Dermatology. 19709 (1), 21-30.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H314-H340-H350

Harmful if swallowed. Causes severe skin burns and eye damage. May cause genetic defects. May cause cancer.

Precautionary Statements: P201-P202-P260-P264b-P270-P281-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use personal protective equipment as required. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Do NOT induce vomiting. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,5988
Beilstein
196453
Hazard Class
8
Packing Group
II
Harmonized Tariff Code
2932.20
TSCA
Yes
RTECS
LV1400000

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