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A17140 2-Adamantanamine hydrochloride, 98+%

CAS Number
10523-68-9
Synonyms
2-Aminoadamantane hydrochloride

Stock No. Size Price ($) Quantity Availability
A17140-03 1g 26.40
A17140-06 5g 78.90
A17140-14 25g 265.00
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2-Adamantanamine hydrochloride, 98+%

MDL
MFCD00074743
EINECS
234-074-2

Chemical Properties

Formula
C10H17N•HCl
Formula Weight
187.71
Melting point
>300°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2?-(carboxymethoxime)-olivomycin I. The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from oxidizing agents.

Literature References

JS Scott.; J deSchoolmeester.; E Kilgour. Novel Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor with Reduced Acyl Glucuronide Liability: The Discovery of 4-[4-(2-Adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic Acid (AZD8329). J. Med. Chem.201255 (22), 10136-10147.

SW Kwon.; SK Kang.; JH Lee.; JH Bok.; CH Kim. Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group. Bioorganic & Medicinal Chemistry Letters. 201121 (1), 435-439.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
4297901
Harmonized Tariff Code
2921.30
TSCA
No
RTECS
AU4375100

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