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1-Piperazineethanol is a hydroxyalkyl substituted pieprazine used in the preparation of pharmaceutical compounds. It is also used as an Intermediate in the manufacture of polyurethane catalysts, corrosion inhibitors, surfactants, synthetic fibers, pharmaceuticals. It is also used to synthesize triethylenediamine.
I Sircar.; SJ Haleen.; SE Burke. Synthesis and biological activity of 4-(diphenylmethyl)-. alpha.-[(4-quinolinyloxy) methyl]-1-piperazineethanol and related compounds. J. Med. Chem..199235 (23), 4442-4449.
HL Yale. Esters of 4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-1-piperazineethanol and related compounds as long-acting antipsychotic agents. Synthesis of the 1-adamantoate, the first crystalline base. 4 J. Med. Chem.197720 (2), 302-304.
Hazard Statements: H315-H318
Causes skin irritation. Causes serious eye damage.
Precautionary Statements: P264b-P280-P302+P352-P305+P351+P338-P310-P332+P313-P362
Wash face, hands and any exposed skin thoroughly after handling Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse.