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1733-12-6 - Cresol Red - o-Cresolsulfonephthalein - A17243 - Alfa Aesar

A17243 Cresol Red

CAS Number
1733-12-6
Synonyms
o-Cresolsulfonephthalein

Size Price ($) Quantity Availability
25g 49.75
100g 142.30
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Cresol Red

MDL
MFCD00005878
EINECS
217-064-2

Chemical Properties

Formula
C21H18O5S
Formula Weight
382.44
Melting point
>300°
Solubility
Soluble in water (slightly at 20°C), 50% ethanol (0.1%), dil. acids, and dil. alkalis. Insoluble in benzene.

Applications

Cresol red is commonly used with lead acetate for the detection of urease after PAGE. It is also used as an indicator with the following transition intervals: pH 1.8 (orange) to pH 2.0 (yellow); pH 7.0 (yellow) to pH 8.8 (violet). Cresol Red is used as a tracking dye in DNA, RNA (agarose) and protein (polyacrylamide) electrophoresis. In agarose, Cresol Red runs with an apparent molecular size of approx. 125 bp DNA. Cresol Red does not inhibit Taq polymerase.

Notes

Transition interval (acid): pH 1.8 (orange) to pH 2.0 (yellow); (alkaline) pH 7.0 (yellow) to pH 8.8 (violet)

Literature References

Robert H. Byrne.; Jabe A. Breland. High precision multiwavelength pH determinations in seawater using cresol red. Deep Sea Research Part A. Oceanographic Research Papers. 1989, 36 (5), 803-810.

M. Neus Piña.; M. Carmen Rotger.; Antoni Costa.; Pablo Ballester.; Evaluation of anion selectivity in protic media by squaramide-Cresol Red ensembles. Pere M. Deyà. Tetrahedron Lett. 2004, 45 (19),3749-3752.

Acid-base indicator: pH 0.2 - 1.8; 7.0 - 8.8.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,2578
Beilstein
343399
Harmonized Tariff Code
2934.99
TSCA
Yes

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